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Acoustic Cell Processing 

A disruptive technology that is scalable, simplifies, reduces costs and improves quality.

Dr. Bart Lipkens

How can invisible ultrasonic waves be used for processing cells?

Dr. Bart Lipkens, Co-founder and CTO of FloDesign Sonics, explains the science behind acoustophoresis and how it can be used to solve big challenges in cell and gene therapy bioprocessing.

How It Works (1,068.26 KB)
File Type: PDF

Advantages of Acoustic Cell Processing

Gentle

The acoustic field used to manipulate cells imparts minimal energy.  Shear forces on cells are negligible as compared to centrifuge or spinning filters. Viability testing for common cell lines have revealed minimal impact.    

Scalable

Autologous or allogeneic, the acoustic platform allows for continuous operation.  No need for sizing up filters or purchasing larger equipment    

Simplifies

We are building out several applications all with the same acoustic engine.  Using a platform technology simplifies training as well as regulatory concerns.  We have also developed our system with a modular design facilitating several applications with one system       

Cost Reduction

Process inefficiencies and materials cost are large contributors to the overall cost of goods.  By developing a modular platform we can reduce processing time. Material costs are potentially saved in the cell selection process

Improves Quality

In addition to providing gentle manipulation of cells, acoustics can provide a magnetic bead free solution in cell selection applications         

Only Acoustics Delivers a Platform Technology

compare-chartSPINNING MEMBRANE FILTERMAGNETIC BEADCENTRIFUGATIONACOUSTIC CELL PROCESSINGCONCENTRATE / WASHCELL SELECTIONCELL RETENTION

How Did We Come Up with This

Put an Acoustic Engine in Your Process